Building the Future of Biodefense

Biothreat intelligence to deter and detect natural, accidental, deliberate and novel biological agents.

ADVISORY
Pakistan reports its 1st wild polio case of 2026 in Sindh
03/05/2026
Pakistan, Sindh

Recommendation: The polio vaccine is more than 99% effective in preventing poliovirus infection. Travelers to Pakistan should verify their polio vaccination status before travel.

Situation: Pakistan confirmed its 1st wild poliovirus case of 2026 in a 4-year-old child from Sujawal district, Sindh. The next national vaccination campaign is planned for April. Poliovirus detections have declined compared to 2024 due to strong 2025 vaccination campaigns, but transmission continues in high-risk areas of Sindh and southern Khyber Pakhtunkhwa, highlighting the need for continued targeted efforts and consistent child vaccination. [Confidence: Very High]

WATCH
Colorado declares measles outbreak after a 3rd case is linked to Broomfield High School
03/05/2026
Colorado, Adams CountyColorado, Broomfield County

Recommendation: Organizations in Adams and Broomfield Counties, Colorado, should inform employees about the potential measles exposures. Organizations should provide flexible work schedules to support employees who need to make vaccine appointments for themselves or their family members. Measles is highly contagious and can quickly spread among unvaccinated individuals in a work environment.

Situation: Health officials reported a 3rd measles case linked to Broomfield High School, and classified the situation as an outbreak. The case is an unvaccinated child from Adams County, and is a known contact of another case tied to Broomfield High, where 2 students were confirmed to have measles (see PHC alerts 3/3 and 3/2). The public may have been exposed at Broomfield Heights Middle School (2/17-19) and Broomfield Community Center (2/19). Exposed individuals should monitor for measles symptoms (7-21 days from exposure). [Confidence: Very High]

WATCH
Measles exposures on Ontario buses and international flights into Toronto
03/05/2026
Canada, Ontario

Recommendation: Organizations in Toronto and York in Ontario, Canada, should inform employees about the possible measles exposures and should provide flexible work schedules to support employees making vaccine appointments for themselves or family members. Measles is highly contagious and can quickly spread among unvaccinated individuals in a work environment.

Situation: Toronto confirmed its 1st measles case of the year in an individual who recently traveled internationally. The public may have been exposed on Avianca Flight #AV579 from Guatemala City to San Salvador (2/22), Avianca Flight #AV324 from San Salvador to Toronto (2/22), and at Toronto Pearson International Airport Terminal 1 Arrivals (2/22). Elsewhere in Ontario, York Region reported potential measles exposure events on York Region Transit Bus Route #16 - 16th Ave (2/23, 2/25-26), York Region Transit Bus Route #25 - Major Mackenzie (2/24), York Region Transit Bus Route #90B - Leslie (2/27), and Cortellucci Vaughan Hospital Emergency Department (2/28). Exposed individuals should monitor for measles symptoms (7-21 days from exposure). [Confidence: Very High]

ADVISORY
1st local dengue case of the year on Easter Island, Chile
03/04/2026
Chile, Region de Valparaiso

Recommendation: Dengue is considered endemic on Easter Island (Rapa Nui), with recurrent, small locally acquired outbreaks reported since 2002. Organizations should reduce mosquito habitats by eliminating sources of standing water and applying insecticides to outdoor water storage containers. Employees can reduce infection risk by wearing clothing that covers skin, using mosquito repellents, and emptying standing water.

Situation: According to media sources, the 1st locally acquired case of dengue fever was confirmed on Rapa Nui, Chile's Easter Island since 2024. The individual contracted the virus on the island and had no recent travel history abroad. In response, health officials activated established protocols to prevent further infections and control potential spread. [Confidence: Very High]

ADVISORY
Avian influenza outbreaks in Maryland, North Carolina, and Wisconsin impact millions of commercial poultry birds
03/04/2026
Maryland, Caroline CountyNorth Carolina, Hyde CountyWisconsin, Jefferson County

Recommendation: The primary impact of highly pathogenic avian influenza (HPAI) outbreaks in commercial flocks is the increased cost of eggs or poultry products when outbreaks become more widespread. Organizations sensitive to egg and poultry prices should have a contingency plan for price volatility. PHC recommends that continuity plans be reviewed and updated in preparation for high-consequence infectious disease threats.

Situation: HPAI was detected at multiple commercial poultry farms in Maryland, North Carolina, and Wisconsin in recent weeks. In Maryland, 2 outbreaks in Caroline County have affected more than 155,000 commercial broiler chickens. North Carolina reported an outbreak in Hyde County impacting nearly 3.3 million commercial table egg layer hens. Meanwhile, Wisconsin confirmed an outbreak in Jefferson County, affecting over 1.2 million commercial table egg birds. [Confidence: Very High]

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