Building the Future of Biodefense
Biothreat intelligence to deter and detect natural, accidental, deliberate and novel biological agents.
ADVISORY
California man from Tulare County dies after contracting West Nile virus
06/25/2025
California, Tulare County
Recommendation: West Nile virus (WNV) activity in California typically occurs in the summer and early fall. Organizations should reduce mosquito habitats by eliminating sources of standing water and applying insecticides to outdoor water storage containers. Employees can reduce infection risk by wearing clothing that covers skin, using mosquito repellents, and emptying standing water.
Situation: California health officials in Tulare County reported a human WNV case, which resulted in the death of an adult male. This is the 1st reported human case in California this year. WNV was also detected in mosquitoes at multiple sites within the county. Residents were advised to take precautions against mosquito bites. [Confidence: Very High]
ADVISORY
Lyme disease cases rise in Berlin as warmer weather extends tick season
06/25/2025
Germany, Land Berlin
Recommendation: Organizations in Berlin, Germany, with employees working outdoors in grassy or wooded areas should remind them that tick bite prevention is important for minimizing exposure risk. Wearing protective clothing, using insect repellent, and conducting tick checks after being in grassy, agricultural, or forested areas protects employees from tickborne diseases.
Situation: As of 6/18, 206 cases of Lyme disease were reported in Berlin, above the pre-pandemic 2015–2019 average of 146 for the same period. Health officials attributed the rise to climate change, which has led to milder winters and warmer springs, extending the tick season and increasing human-tick contact. Berlin reported 972 Lyme disease cases in 2024, 984 in 2023, and 807 in 2022. [Confidence: Very High]
ADVISORY
Cambodia reports a new H5N1 human case, the 4th in the past month and 7th of 2025
06/24/2025
Cambodia, Siem Reap
Recommendation: This new H5N1 case in an individual with exposure to sick birds in Cambodia does not change PHC's recommendations for organizations. No human-to-human spread of avian influenza has been detected. Organizations should follow the recommendations provided in the PHC analysis on 1/10 and 2/13, including lowering barriers to seasonal flu vaccines for their employees. Employees should avoid live-animal markets and not have contact with or consume diseased poultry.
Situation: Cambodia confirmed its 7th H5N1 human case this year. The case was reported from Siem Reap Province in an adult who had exposure to sick and dead birds before symptom onset. She is currently hospitalized and is in critical condition. 4 of the 7 H5N1 human cases in Cambodia were reported in the past month. See PHC alerts on 6/23, 6/16, 5/28, 3/24, and 2/26 for earlier info. [Confidence: Very High]
WATCH
Mexico reports 4 more measles deaths, totaling 9 for 2025
06/24/2025
Mexico
Recommendation: Organizations in Mexico should provide flexible work schedules to support employees making vaccine appointments for themselves or family members. Measles is highly contagious and can quickly spread among unvaccinated individuals in a work environment.
Situation: Mexico reported 4 more measles deaths, totaling 9 for 2025 (8 in Chihuahua and 1 in Sonora). Cases continue to fluctuate in recent weeks, but remain below levels seen in April. So far this year, 5,410 probable measles cases were reported, of which 2,597 were confirmed. Chihuahua remains the most affected state. See PHC alerts on 6/16, 6/4, 5/22, 5/2, and 4/18 for earlier info. [Confidence: Very High]
WATCH
Bolivia's measles outbreak surges to 50 confirmed cases and over 300 suspected cases
06/24/2025
Bolivia
Recommendation: Organizations in Bolivia should provide flexible work schedules to support employees making vaccine appointments for themselves or family members. Measles is highly contagious and can quickly spread among unvaccinated individuals in a work environment.
Situation: The measles outbreak in Bolivia reached 50 confirmed cases and over 300 suspected cases. The outbreak started in late April with an imported case from Russia, where the disease then spread among a Mennonite community, following exposures at 2 religious gatherings in Santa Cruz. Of the 50 confirmed cases, 47 were reported in Santa Cruz, with the remaining 3 cases in La Paz (2) and Potosi (1). Health officials implemented vaccination blockade brigades within a 5-block radius of families that test positive. See PHC alerts on 6/9 and 6/20 for earlier info. [Confidence: Very High]
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PHC Navigator
PHC Navigator is a biothreat intelligence engine built on expert-curated and proprietary data and models that provides actionable intelligence and insights
PHC Vector
PHC Vector provides direct programmatic access to PHC Global intelligence to simplify an increasingly complex biodefense landscape
